Yes, you can do that. Usually, the Best of 4 subjects should include those in which you have scored the most in your Class 12 result. If English is your first language/ medium of education, then marks obtained in that will be mandatory. But you will need to include that subject that you wish to pursue in your UG programme. For eg., say your Best of 4 subjects include - English, Agriculture, Pol. Science & Hindi, but you wish to pursue Geography (H) for UG, then it is mandatory for you to include your Class 12 Geography marks to calculate your Class 12 CGPA or percentage.
Our suggestion will be to apply to these colleges of your choice right now, as admissions are open currently. Whenever the CBSE results are out, you can take action accordingly. You can also apply to all colleges of your choice using a Single Application Form. This form allows you to apply to 500+ colleges of your choice! What's more, you can even add your shortlisted colleges and apply in one go, thus saving time, energy & money. There's a 20% discount on all applications currently, so don't lose out! Book your seat in a college of your choice immediately. Good luck!