GPAT 2025 Topic-Wise Weightage: Subject-wise weightage, No. of Questions Asked

Ritoprasad Kundu

Updated On: May 14, 2025 10:56 AM | GPAT

In the GPAT exam, important topics like Titrimetric Analysis, Aldehydes, Ketones and Carboxylic Acid, Biomolecules, Chemotherapy, Parenteral Preparation, etc. carry the majority of weightage. Find more details on this below.
GPAT 2025 Topic-Wise Weightage

If you are preparing for the upcoming GPAT exam , you must be wondering about important topics for the exam or which topics carry the most weightage. While you need to be thorough with your GPAT exam preparation , covering the GPAT Syllabus and studying the GPAT best books , on the other hand, you also need to know about the GPAT important topics and which subjects carry the most weightage.

The high-weightage topics for GPAT exam include Titrimetric Analysis, Aldehydes, Ketones and Carboxylic Acid, Biomolecules, Chemotherapy, Parenteral Preparation, Micromeritics, Introduction to Biopharmaceutics, Surface and Interfacial Phenomena, to name a few.

By a thorough analysis of the GPAT past year papers , you can identify the types of questions asked, and thereby, allocate time for those portions to secure a rank in the exam. Moreover, with the help of these crucial topics, you can also build a focused and efficient preparation strategy for GPAT . Let us analyse topic-wise weightage given to each subject in the exam.

Also Read:

Topic Wise Weightage for GPAT Exam

Check the important topics for GPAT from the below table.

Subject

Expected Number of Questions

Expected Weightage

Pharmacology

15 - 20 Questions

20 - 25%

Pharmaceutics

10 - 15 Questions

15 - 20%

Pharmaceutical Chemistry

10 - 12 Questions

12 - 15%

Pharmacognosy

8 - 10 Questions

10 - 12%

Pharmaceutical Analysis

6 - 8 Questions

8 - 10%

Biochemistry

4 - 6 Questions

5 - 8%

Clinical Pharmacy / Therapeutics

4 - 5 Questions

5 - 7%

Microbiology & Biotechnology

3 - 4 Questions

3 - 5%

Pathophysiology

2 - 3 Questions

2 -3%

Physical Chemistry

2 - 3 Questions

2 -3%

Regulatory Affairs

2 - 3 Questions

2 -3%

Also Read:

Important Topics for GPAT Exam

You can check the high weightage topics for GPAT from the table below.

Subject

High Weightage Topics

Expert Opinion

Pharmacology

  • General Pharmacology
  • Autonomic Nervous System (ANS)
  • Central Nervous System (CNS)
  • Cardiovascular system drugs
  • Chemotherapy (Antibiotics, Anticancer, Antitubercular, etc.)
  • Endocrine Pharmacology
  • Toxicology
  • Drug Interactions
  • Adverse Drug Reactions (ADRs)

High weightage due to its clinical relevance. Expect scenario-based and mechanism questions.

Pharmaceutics

  • Physical Pharmacy
  • Pharmaceutical Engineering
  • Biopharmaceutics & Pharmacokinetics
  • Dosage Forms (Tablets, Capsules, Parenterals, Aerosols, etc.)
  • Microencapsulation
  • Novel Drug Delivery Systems
  • Rheology
  • Stability of formulations
  • Bioavailability & Bioequivalence
  • Pharmaceutical calculations

Often includes numerical problems, especially in Biopharmaceutics.

Pharmaceutical Chemistry

  • Basic Organic Chemistry Principles
  • Stereochemistry
  • Drug Design & SAR (Structure-Activity Relationships)
  • Synthesis of key drugs (e.g., paracetamol, sulfonamides, fluoroquinolones)
  • Antibacterials, Antivirals, Antifungals
  • CNS & CVS acting agents
  • Prodrugs and bioisosteres

Focus on drug synthesis, classification, and SAR

Pharmacognosy

  • Basics of crude drugs
  • Classification of natural products
  • Techniques like TLC, HPTLC, etc.
  • Alkaloids, Glycosides, Tannins, Terpenoids
  • Methods of extraction and purification
  • Herbal drugs and traditional systems (Ayurveda, Siddha, Unani)
  • Plant tissue culture
  • Adulteration of crude drugs

Can include botany-based and chemical constituent identification questions.

Pharmaceutical Analysis

  • UV, IR, NMR, Mass Spectrometry
  • Titrations (Acid-base, Redox, Complexometric)
  • Chromatography (TLC, HPLC, GC)
  • Spectroscopy
  • Quality control and assurance
  • Limit tests and assay methods

Analytical instruments and interpretation are frequently asked.

Biochemistry

  • Enzymes and Enzyme Kinetics
  • Carbohydrate, Protein, Lipid metabolism
  • Vitamins & Coenzymes
  • Hormones
  • Nucleic acid metabolism
  • Bioenergetics (ATP cycle)

Metabolic pathways (e.g., Glycolysis, TCA) are common question areas.

Clinical Pharmacy & Therapeutics

  • Therapeutic Drug Monitoring
  • Clinical Trials & Phases
  • Pharmacovigilance
  • Patient Compliance
  • Rational Drug Use
  • Disease Management

Case-based questions are common in this section

Microbiology

  • Sterilization methods
  • Culture media and techniques
  • Microbial genetics
  • Pathogens & infections
  • Preservation of pharmaceutical products

Biotechnology

  • rDNA Technology
  • Fermentation
  • Monoclonal antibodies
  • PCR, ELISA
  • Gene Therapy
  • Vaccines

Pathophysiology

  • Basic mechanisms of diseases
  • Inflammation, Immunity
  • Major disorders: Diabetes, Hypertension, Asthma, Cancer

Pharmaceutical Jurisprudence

  • D & C Act 1940
  • Pharmacy Act 1948
  • NDPS Act
  • Schedule H, X drugs
  • Intellectual Property Rights (IPR), Patents

Related Article: GPAT vs NIPER JEE - Which is Best for You?

Previous Year GPAT Question Paper Analysis: No. of Questions Asked

This section is quite important as it highlights the number of questions that were asked in the last 15 years from very important topics. Check the table below to know more.

Topics

Number of Questions in last 15 Years

Titrimetric Analysis

32

UV-Visible and Fluriometry

26

Aldehydes, Ketones and Carboxylic Acid

32

Biomolecules

33

Chemotherapy

101

Parenteral Preparation

26

Tablets

54

Surface and Interfacial Phenomena

23

Introduction to Biopharmaceutics

24

General Pharmacology

74

HAP

89

Central Nervous System

57

Alkaloids

24

Quality Control of Crude Drugs

23

Glycosides

23

Best Books for GPAT Preparation

Check the list of books with their respective authors for GPAT exam preparation.

Name of the Book

Name of the Author

Organic Chemistry

Morrison and Boyd

Essentials of Medical Pharmacology

K.D. Tripathi

The Pearson Guide to GPAT and Other Entrance Examination in Pharmacy

Akaberi Shah Baser, S. Manikandan

Textbook of Pharmacognosy

C.K. Kokate, A.P. Purohit, S.B. Gokhale

GPAT: A Companion

Nazma Nigar

Textbook of Medicinal Chemistry

S.N. Pandeya & J.R. Dimmock

Physical Pharmaceutics

C.V.S. Subrahmanyam

Pathophysiology of Disease: An Introduction to Clinical Medicine

Gary D. Hammer, Stephen J. McPhee

Pharmacognosy

Trease and Evans

Physical Pharmacy

Alfred Martin

Remington: The Science and Practice of Pharmacy

Loyd Allen Jr.

GPAT Challenger

Dr. Sachin C. Itkar

Comprehensive Medicinal Chemistry

Ashutosh Kar

The Theory and Practice of Industrial Pharmacy

Lachman, Lieberman, and Kanig

Rang & Dale’s Pharmacology

H.P. Rang, M.M. Dale

GPAT Cracker

Rahul Hajare

Related Articles:

With the help of the high-weightage topics for GPAT, you can devise an efficient preparation plan along with decisive time management skills, enhancing your conceptual clarity and understanding and improving your performance in the exam. Therefore, it is wise to do good research on topics that are usually asked before preparing for the exam. At the same time, in the last 2 months, it is also advised to focus on these important topics to score well in the GPAT exam.

Get help with all your doubts on the GPAT exam by calling us on our number 1800-572-9877. You can also post your questions in the QnA zone to be answered by experts. For more help and information, fill up the Common Application Form .

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FAQs

What are some of the key topics from Microbiology?

Some of the important topics from Microbiology are Sterilization methods, Culture media and techniques, Microbial genetics, Pathogens & infections and Preservation of pharmaceutical products. 

 

How many questions are expected from Pharmaceutical Chemistry?

From Pharmaceutical Chemistry, it is expected that 10 to 12 questions will be asked.

What are the high weightage topics for GPAT?

The high weightage topics include Titrimetric Analysis, Aldehydes, Ketones and Carboxylic Acid, Biomolecules, Chemotherapy, Parenteral Preparation, Micromeritics, Introduction to Biopharmaceutics, Surface and Interfacial Phenomena etc. 

 

What type of questions can be asked from Pharmacognosy?

From the analysis of previous year question papers you can expect botany based and chemical constituent identification questions in the GPAT exam.

 

What are some of the practice books for GPAT?

Some of the practice books for the GPAT exam are GPAT: A Companion by Nazma Nigar, GPAT Cracker by Ranjan Patel, MCQs in Pharmacy by Manoj Chaturvedi and GPAT Challenger by Dr. Sachin C. Itkar. 

 

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