GPAT Syllabus 2019

Deepika Narwal Updated On: 04 Oct, 2018 15:57 IST

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01 Nov-30 Nov, 2018

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GPAT 2019 Syllabus

GPAT 2019 Syllabus is prescribed by NTA and it can be changed by the authority from year to year. GPAT 2019 Syllabus covers many aspects related to pharmaceuticals, such as Chemistry, Engineering, Management, Technology and even legal and regulatory knowledge about pharmaceutical business.

Subject

Topics

Pathophysiology

Basic principles of cell injury and adaptation, Basic mechanism of inflammation and repair, Hypersensitivity, Autoimmunity and diseases of immunity, Neoplastic diseases, Shock, Biological effects of radiation, Protein-calorie malnutrition, vitamins, Obesity and starvation, Pathophysiology of common diseases, Infectious diseases

Biopharmaceutics and Pharmacokinetics

Bio-pharmaceutics, Bio-availability and bio-equivalence, Bio-pharmaceutical statistics

Organic Chemistry

General principles, Different classes of compounds, Protection and deprotection of groups, Aromaticity and aromatic chemistry, Different aromatic classes of compounds, Polycyclic aromatic hydrocarbons, Carbonyl chemistry, Heterocyclic chemistry, Bridged rings, Kinetic and thermodynamic control, Stereochemistry, Carbohydrates, Amino acids and proteins, Organometallic chemistry, Pericyclic reactions

Pharmaceutical Chemistry

Pharmaceutical impurities, Monographs, Isotopes, Therapeutic classes of drugs, Drug metabolism, Various classes of therapeutic agents, Different classes of therapeutic drugs

Pharmaceutics

Pharmacy profession, Introduction to pharmaceuticals, Introduction to dosage form, Route of administration, ADME, Sources of drug information, Allopathic dosage form, Crude extract, Allergenic extract Ayurvedic system of medicine, Homeopathic system of medicine, Biological products, GMP, Pharmaceutical plant, location, layout Dosage form necessities and additives, Powders, Capsules, Tablets Parenterals – products requiring sterile packaging, Suspensions Emulsions, Suppositories, Semisolids, Liquids, Pharmaceutical aerosols Ophthalmic preparations, Preformulations , Radio pharmaceuticals Stability of formulated products, Kinetic principles and stability testing Prolonged action pharmaceuticals, Novel drug delivery system, Cosmetics, Packaging material, GMP and validation, Pilot plant scale-up techniques

Pharmacology

General pharmacology, Pharmacology for peripheral nervous system, Pharmacology of cardiovascular system, Drugs acting on urinary system, Drugs acting on respiratory system, Pharmacology of central nervous system, Pharmacology of endocrine system, Chemotherapy, Autacoids and their antagonists, Pharmacology of drugs acting on gastrointestinal tract, Chronopharmacology, Immunopharmacology, Chemotherapy of malignant diseases, Peptides and proteins as mediators, Nitric oxide, Vitamins and minerals, Principles of toxicology

Pharmacognosy

Introductory Pharmacognosy, Classification of crude drugs, Sources of crude drugs, Factors influencing quality of crude drugs, Techniques in microscopy, Introduction to phytoconstituents, Principles of plant classification, Pharmaceutical aids, Animal products, Plant products, Toxic drugs, Enzymes, Natural pesticides and insecticides, Adulteration and evaluation of crude drugs, Quantitative microscopy, Biogenetic pathways, Carbohydrates and lipids, Tannins, Volatile oils, Resinous drugs, Glycocides, Alkaloids, Herbarium, Extraction and isolation techniques, Phytopharmaceuticals, Quality control and standardization of herbal drugs, Herbal formulations, Worldwide trade of crude drugs and volatile drug, Plant biotechnology, Herbal cosmetics, Traditional herbal drugs, Plant-based industries and research institutes in India Patents

Pharmaceutical Analysis

Importance of quality control in pharmacy, Acid-base titrations, Non-aqueous titrations, Oxidation-reduction titrations, Precipitation titrations, Complexometric titrations, Gravimetry, Extraction techniques , Potentiometry, Miscellaneous methods of analysis, Calibration General principles of spectroscopy, Ultraviolet-visible spectrometry Spectrofluorimetric, Flame photometry and atomic absorption spectrometry, Infrared spectrometry, Proton nuclear magnetic resonance spectrometry, Mass spectrometry, Polarography, Nephelometry and turbidimetry, Chromatography

Physical Chemistry

Composition and physical states of matter, Colligative properties, Thermodynamics, Chemical equilibria, Phase rule, Refractive index, Solutions, Electrochemistry, Ionic equilibrium, Kinetics

Physical Pharmacy

Matter, properties of matter, Micromeritics and powder rheology, Surface and interfacial phenomenon, Viscosity and rheology, Dispersion systems, Complexation, Buffer, Solubility

Biochemistry

Cell, Carbohydrates, Proteins, Lipids, Vitamins, Biological oxidations and reductions, Enzymes, Nucleic Acids, Hereditary diseases

Biotechnology

Plant cell and tissue culture, Animal cell structure, Fermentation technology and industrial microbiology, Recombinant DNA Technology, Process and applications, Biotechnology-derived products, Proteomics, Formulation of proteins and peptides

Microbiology

Introduction to microbiology, Microscopy and staining technique, Biology of microorganisms, Fungi and viruses, Asceptic technique, Sterilization and disinfection, Microbial spoilage, Immunology and health, Vaccines and sera, Microbial assay

Pharmaceutical Jurisprudence

Historical background Drug legislation in India, Code of Ethics for Pharmacists, The Pharmacy Act 1948 (inclusive of recent amendments), Drugs and Cosmetics Act 1940, Rules 1945, including New Drug applications, Narcotic Drugs and Psychotropic Substances Act, and Rules thereunder, Drugs and Magic Remedies (Objectionable Advertisements) Act 1954, Medicinal and Toilet Preparations (Excise Duties) Act 1955, Rules 1976, Medical Termination of Pregnancy Act 1970 and Rules 1975, Prevention of Cruelty to Animals Act 1960, Drug (Price Control) Order, Shops and Establishment Act, Factory Act, Consumer Protection Act, Indian Pharmaceutical Industry- An Overview, Industrial Development and Regulation act 1951, Introduction to Intellectual Property Rights and Indian Patent Act 1970,An Introduction to Standard Institutions and Regulatory Authorities such as BIS, ASTM, ISO, TGA, USFDA, MHRA, ICH, WHO, Minimum Wages Act 1948, Prevention of Food Adulteration Act 1954 and Rules 1955.

Clinical pharmacy and therapeutics

General Principles, preparation, maintenance, analysis of observational records in Clinical Pharmacy, Clinical trials, type and phases of clinical trials, placebo, ethical and regulatory issues including Good clinical practice in clinical trials, Therapeutic drug monitoring, adverse drug reaction (ADR), types of ADR, Mechanism of ADR. Drug interaction, Monitoring and reporting of ADR and its significance, Drug information services, Drug interactions, Drug interaction in pediatric and geriatric patients, drug treatment during pregnancy, lactation and menstruation, Pharmacovigilance, Therapeutic drug monitoring, Nutraceuticals, essential drugs and rational drug usage, Age-related drug therapy: concept of posology, drug therapy for neonates, pediatrics and geriatrics. Drugs used in pregnancy and lactation, Drug therapy in gastrointestinal, hepatic, renal, cardiovascular and respiratory Disorders, Drug therapy for neurological and psychological disorders, Drug therapy in infections of the respiratory system, urinary system, infective meningitis, TB, HIV, malaria, and filaria. Drug therapy for thyroid and parathyroid disorders, diabetes mellitus, menstrual cycle disorders, menopause and male sexual dysfunction, Drug therapy for malignant disorders like leukemia, lymphoma and solid tumors, Drug therapy for rheumatic, eye and skin disorders.

Pharmaceutical Management

Introduction to management, Planning, and forecasting, Organization, Research management, Inventory management, Communication, Marketing research, Leadership and motivation, Human resource development, GATT, WTO and TRIPS, Standard institutions and regulatory authorities

Pharmaceutical Engineering

Fluid flow, Heat transfer, Evaporation, Distillation, Drying, Size reduction and size separation, Extraction, Mixing, Crystallization, Filtration and centrifugation, Dehumidification and humidity control, Refrigeration and air conditioning, Material of constructions, Automated process control systems, Industrial hazards and safety precautions

Dispensing and Hospital Pharmacy

Introduction to laboratory equipment, weighting methodology, handling of prescriptions, labeling instructions for dispensed products. Preparations based on percolation process. Preparations based on maceration process. Study of difference between marketed and dispensed products of different dosage forms. Posological calculations involved in the calculation of dosage for infants. Enlarging and reducing formula, displacement value. Preparations of formulations involving allegation, alcohol dilution, isotonic solution.

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