To be eligible for the B.Tech degree program at Kamala Institute of Technology & Science in Karimnagar, candidates must have completed their 10+2 education with a minimum of 50% aggregate marks in the science stream. Additionally, candidates must have a valid score in either the state-level engineering entrance exam or national level exams such as JEE Main or TS EAMCET. Meeting these eligibility criteria is essential for admission to the B.Tech program at Kamala Institute of Technology & Science, where students can receive a quality education and practical training in engineering disciplines.