NIPER JEE Syllabus 2018

Nidhi Bahl Updated On: 20 Aug, 2018 16:57 IST

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NIPER JEE 2018 Syllabus

Candidates appearing for NIPER JEE 2018 should have a good understanding about the syllabus of the exam. NIPER JEE 2018 syllabus mentions all the topics/chapters that candidate must study to prepare for the entrance exam. On the basis of syllabus, various questions are asked in the NIPER JEE 2018.

The detailed syllabus is mentioned below.

Syllabus of Phytochemistry

Fischer projection formulas

Biological sources of important classes of natural products. (Selected ones only)

Primary metabolites, their examples

Methods of extraction, isolation and characterization of natural products

Important therapeutic classes: antidiabetics, hepatoprotectives, immmunomodulators, neutraceuticals, natural products for gynaecological disorders, anti-cancer, anti-viral (mainly anti-HIV), adaptogens etc

Secondary metabolites, various classes of secondary metabolites (eg. Alkaloids, glycosides, tannins, lignans, saponins, lipids, flavonoids, coumarins, etc.)

Dietary antioxidants, Marine natural products, Plant growth regulators

Some knowledge about types and preparation of ayurvedic formulatios like asava, arista etc

What is difference between natural products and pharmacognosy?

Biosynthetic pathways.

Various separation techniques used for isolation of natural products

Standardization of natural products, analytical pharmacognosy

Syllabus of Natural Products

Primary metabolites

Important therapeutic classes

Biosynthetic pathways

Marine natural products

Methods of extraction, isolation and characterization of natural products

Dietary antioxidants

Secondary metabolites

Spectroscopy

Plant growth regulators

Phytochemistry

Syllabus of Aptitude

Simple Mathematics

logical reasoning and data analysis,

Questions based on English language

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Syllabus of Stereochemistry

Biological sources of important classes of natural products

Bioassay methods

Drug delivery systems (DDS)

Dosage forms

Chemotherapy and pathophysiology

(TDDS)

Pharmacokinetics

Pharmacological effect, desired, undesired, toxic, adverse effects

Fischer, sawhorse and newmon projection formulas

Mechanism of drug action

Bioavailability, bioequivalence, various factors of ADME

Evaluation of formulation, principles and methods of release control in oral formulations

Additives of formulation, types, examples, advantages, disadvantages, drug excipient interaction, incompatibility, various types of incompatibilities

Drug interactions, agonist, antagonist, protein binding, drug distribution, distribution volume, excretion pathways

Pharmaceutics and formulation (Pharmaceutical Technology)

Standardization of natural products

Pharmacology and toxicology

Various adrenergic, cholinergic and other receptors

Pharmacodynamics

Drug metabolism

Bioavailability, bioequivalence studies

Compartmental modeling

Pharmacological screening

Drug-receptor interaction

Packaging

Diseases

Detailed study of CNS pharmacology Transdermal drug delivery systems

Dosage form development- stages, implications of dosage form

Carriers in DDS

Parenteral

Complexation

Viscosity measurements

Solubilization

Drug targeting

 Syllabus of Biotechnology and Biochemistry

DNA synthesis

Classification of enzymes and their functions mechanism of action of

Genetic Engineering

Gel electrophoresis

Pharmaceutical technology

Blotting techniques(Western, southern)

Immunoassays, protein

Gene cloning

rDNA technology

RNA synthesis

Syllabus of Chemistry

Aromaticity

Carbohydrates classification

E and Z isomerism

Ester hydrolysis

Pericyclic reactions

Reactions like Cannizarro’s reaction

Tautomerism

Spectroscopy

Introduction to thermal methods of analysis

type of stereoisomer

Basic organic chemistry and biochemistry Stereochemistry

Chromatography

Hybridization

Imine-enamine

Keto-enol tautomerism

Medicinal chemistry and Bulk Drugs

Introduction to Redox reactions

IUPAC nomenclature

Mutarotation

Osazone test

Amino acids proteins

Basic methods of synthesis of various organic compounds

Named reactions

Various Heterocycles, Heterocycle synthesis, reactions

Common condensation reactions like Aldol, Claisen Perkin, Dickmann, Darzen

Reaction kinetics, first second third and pseudo first order reactions, radio labeling for determination of mechanism.

Resolution methods

R and S nomenclature

Racemic mixture

Huckel’s rule reaction mechanisms-

Syllabus of Gene expression

Transcription, translation

Replication

Mutation

Recombination, bacteriophages

Syllabus of Cloning

Methods, isolation of nucleic acids, enzymes in cloning

Fermentation

Syllabus of Pharmacology

partial agonist, protein binding, drug distribution, distribution volume, excretion pathways etc

Drug interactions, agonist, antagonist, Mechanism of drug action, drug-receptor interaction

Bioavailability, bioequivalence, various factors of ADME

Drug metabolism: various pathways and other details

Chemotherapy and pathophysiology- knowledge of antibiotics, their mode of action and the microorganisms responsible for various common diseases

Various adrenergic, cholinergic and other receptors

Diseases: study of the pharmacology of the diseases and drugs used with mode of action especially of diabetes, malaria, leishmaniasis, TB, hypertension, myocardial ischemia, inflammation, and immunomodualtion

Bioassay methods, various requirements. Brief knowledge of the statistical tests

Pharmacokinetics, pharmacodynamics, pharmacological effect, desired, undesired, toxic, adverse effects

Study of basis of threshold areas of work in NIPER in pharmacology dept. Mentioned in brochure

Detailed study of CNS pharmacology specially opiod receptors

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Syllabus of Pharmaceutical analysis

Crystallinity, polymorphism, solvates and hydrates, crystal habits, porosity, surface area flow properties

Osmolality, osmolality, osmotic pressure, conductivity, Preservatives, Media for bioassay

NMR Peaks

Particle sizing

GC

Mass

Tests: physical and chemical tests, limit tests, microbiological tests, biological tests, disintegration and dissolution tests

Preformulation, cyclodextrin inclusion compounds

LCMS

IR

Dosage forms, Stages of dosage form development

Stability testing of pharmaceuticals, various stability tests, kinetic studies, shelf life determination, thermal stability, formulation stability

HPLC

Spectroscopic methods

Chromatography- detailed QA and QC: GLP, TQM, ISO system

Transdermal drug delivery systems (TDDS): principles, absorption enhancers, evaluation of TDDS

NMR

Fluorimetry

Electrophoresis

UV-Visible

Drug delivery systems (DDS): NDDS models, osmotic pumps, various release patterns

Carriers in DDS: polymers and their classification, types, carbohydrates, surfactants, proteins, lipids, prodrugs etc

Solubility

Various analytical techniques

XRD

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